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PCIF1, the only methyltransferase of N6,2-O-dimethyladenosine

N6-methyladenosine(m6A), is the most abundant post-transcriptional modification of mRNA in biology. When the first nucleotide after the m7G cap is adenosine, it is methylated at the N6 position to form N6,2-O-dimethyladenosine (m6Am). m6Am is a reversible modification located at the first transcribe...

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Detalles Bibliográficos
Autores principales: Wu, Yuting, Pu, Xi, Wu, Sihui, Zhang, Yiran, Fu, Shengqiao, Tang, Haowen, Wang, Xu, Xu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544176/
https://www.ncbi.nlm.nih.gov/pubmed/37779183
http://dx.doi.org/10.1186/s12935-023-03066-7