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PCIF1, the only methyltransferase of N6,2-O-dimethyladenosine

N6-methyladenosine(m6A), is the most abundant post-transcriptional modification of mRNA in biology. When the first nucleotide after the m7G cap is adenosine, it is methylated at the N6 position to form N6,2-O-dimethyladenosine (m6Am). m6Am is a reversible modification located at the first transcribe...

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Detalles Bibliográficos
Autores principales:	Wu, Yuting, Pu, Xi, Wu, Sihui, Zhang, Yiran, Fu, Shengqiao, Tang, Haowen, Wang, Xu, Xu, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544176/ https://www.ncbi.nlm.nih.gov/pubmed/37779183 http://dx.doi.org/10.1186/s12935-023-03066-7

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