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Antigen-specific decidual CD8(+) T cells include distinct effector memory and tissue-resident memory cells

Maternal decidual CD8(+) T cells must integrate the antithetical demands of providing immunity to infection while maintaining immune tolerance for fetal and placental antigens. Human decidual CD8(+) T cells were shown to be highly differentiated memory T cells with mixed signatures of dysfunction, a...

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Detalles Bibliográficos
Autores principales: Mahajan, Shweta, Alexander, Aria, Koenig, Zachary, Saba, Nicholas, Prasanphanich, Nina, Hildeman, David A., Chougnet, Claire A., DeFranco, Emily, Andorf, Sandra, Tilburgs, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544202/
https://www.ncbi.nlm.nih.gov/pubmed/37681414
http://dx.doi.org/10.1172/jci.insight.171806