Impaired 1,25-dihydroxyvitamin D(3) action underlies enthesopathy development in the Hyp mouse model of X-linked hypophosphatemia

X-linked hypophosphatemia (XLH) is characterized by high serum fibroblast growth factor 23 (FGF23) levels, resulting in impaired 1,25-dihydroxyvitamin D(3) (1,25D) production. Adults with XLH develop a painful mineralization of the tendon-bone attachment site (enthesis), called enthesopathy. Treatme...

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Detalles Bibliográficos
Autores principales: Rana, Rakshya, Baker, Jiana T., Sorsby, Melissa, Jagga, Supriya, Venkat, Shreya, Almardini, Shaza, Liu, Eva S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544216/
https://www.ncbi.nlm.nih.gov/pubmed/37490334
http://dx.doi.org/10.1172/jci.insight.163259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544216/
https://www.ncbi.nlm.nih.gov/pubmed/37490334
http://dx.doi.org/10.1172/jci.insight.163259

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