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Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques

INTRODUCTION AND METHODS: To understand the relationship between immunovirological factors and antiretroviral (ARV) drug levels in lymph nodes (LN) in HIV therapy, we analyzed drug levels in twenty-one SIV-infected rhesus macaques subcutaneously treated with daily tenofovir (TFV) and emtricitabine (...

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Detalles Bibliográficos
Autores principales: Srinivasula, Sharat, Degrange, Paula, Perazzolo, Simone, Bonvillain, Andrew, Tobery, Amanda, Kaplan, Jacob, Jang, Hyukjin, Turnier, Refika, Davies, Michael, Cottrell, Mackenzie, Ho, Rodney J. Y., Di Mascio, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544331/
https://www.ncbi.nlm.nih.gov/pubmed/37790938
http://dx.doi.org/10.3389/fimmu.2023.1213455