Pathway2Targets: an open-source pathway-based approach to repurpose therapeutic drugs and prioritize human targets

BACKGROUND: Recent efforts to repurpose existing drugs to different indications have been accompanied by a number of computational methods, which incorporate protein-protein interaction networks and signaling pathways, to aid with prioritizing existing targets and/or drugs. However, many of these ex...

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Detalles Bibliográficos
Autores principales: Dobbs Spendlove, Mauri, M. Gibson, Trenton, McCain, Shaney, Stone, Benjamin C., Gill, Tristan, Pickett, Brett E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544355/
https://www.ncbi.nlm.nih.gov/pubmed/37790614
http://dx.doi.org/10.7717/peerj.16088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544355/
https://www.ncbi.nlm.nih.gov/pubmed/37790614
http://dx.doi.org/10.7717/peerj.16088

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