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Pathway2Targets: an open-source pathway-based approach to repurpose therapeutic drugs and prioritize human targets
BACKGROUND: Recent efforts to repurpose existing drugs to different indications have been accompanied by a number of computational methods, which incorporate protein-protein interaction networks and signaling pathways, to aid with prioritizing existing targets and/or drugs. However, many of these ex...
Autores principales: | Dobbs Spendlove, Mauri, M. Gibson, Trenton, McCain, Shaney, Stone, Benjamin C., Gill, Tristan, Pickett, Brett E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544355/ https://www.ncbi.nlm.nih.gov/pubmed/37790614 http://dx.doi.org/10.7717/peerj.16088 |
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