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clrDV: a differential variability test for RNA-Seq data based on the skew-normal distribution

BACKGROUND: Pathological conditions may result in certain genes having expression variance that differs markedly from that of the control. Finding such genes from gene expression data can provide invaluable candidates for therapeutic intervention. Under the dominant paradigm for modeling RNA-Seq gen...

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Detalles Bibliográficos
Autores principales: Li, Hongxiang, Khang, Tsung Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544356/
https://www.ncbi.nlm.nih.gov/pubmed/37790621
http://dx.doi.org/10.7717/peerj.16126