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Integrative bioinformatics analysis and experimental validation of key biomarkers for risk stratification in primary biliary cholangitis

BACKGROUND: Primary biliary cholangitis (PBC) is an autoimmune liver disease, whose etiology is yet to be fully elucidated. Currently, ursodeoxycholic acid (UDCA) is the only first-line drug. However, 40% of PBC patients respond poorly to it and carry a potential risk of disease progression. So, in...

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Detalles Bibliográficos
Autores principales: Tian, Siyuan, Hu, Yinan, Zhang, Miao, Wang, Kemei, Guo, Guanya, Li, Bo, Shang, Yulong, Han, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544390/
https://www.ncbi.nlm.nih.gov/pubmed/37784152
http://dx.doi.org/10.1186/s13075-023-03163-y