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Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos

BACKGROUND: The high incidence of aneuploidy in early human development, arising either from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss, miscarriage, and stillbirth following natural conception as well as in vitro fertilization (IVF). Preimplantation genetic tes...

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Detalles Bibliográficos
Autores principales: McCoy, Rajiv C., Summers, Michael C., McCollin, Abeo, Ottolini, Christian S., Ahuja, Kamal, Handyside, Alan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544495/
https://www.ncbi.nlm.nih.gov/pubmed/37779206
http://dx.doi.org/10.1186/s13073-023-01231-1