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Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos
BACKGROUND: The high incidence of aneuploidy in early human development, arising either from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss, miscarriage, and stillbirth following natural conception as well as in vitro fertilization (IVF). Preimplantation genetic tes...
Autores principales: | McCoy, Rajiv C., Summers, Michael C., McCollin, Abeo, Ottolini, Christian S., Ahuja, Kamal, Handyside, Alan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544495/ https://www.ncbi.nlm.nih.gov/pubmed/37779206 http://dx.doi.org/10.1186/s13073-023-01231-1 |
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