Inhibitory mechanism of vortioxetine on CYP450 enzymes in human and rat liver microsomes

Vortioxetine is a novel anti-major depression disorder drug with a high safety profile compared with other similar drugs. However, little research has been done on drug-drug interactions (DDI) about vortioxetine. In this paper, the inhibitory effect of vortioxetine on cytochrome P450 (CYP450) and th...

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Detalles Bibliográficos
Autores principales: Zhan, Yunyun, Wang, Anzhou, Yu, Yige, Chen, Jie, Xu, Xinhao, Nie, Jingjing, Lin, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544575/
https://www.ncbi.nlm.nih.gov/pubmed/37790811
http://dx.doi.org/10.3389/fphar.2023.1199548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544575/
https://www.ncbi.nlm.nih.gov/pubmed/37790811
http://dx.doi.org/10.3389/fphar.2023.1199548

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