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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

Elucidating the mechanisms of resistance to immunotherapy and developing strategies to improve its efficacy are challenging goals. Bioinformatics analysis demonstrates that high CDK6 expression in melanoma is associated with poor progression-free survival of patients receiving single-agent immunothe...

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Detalles Bibliográficos
Autores principales: Gao, Xueliang, Wu, Yongxia, Chick, Joel M., Abbott, Andrea, Jiang, Baishan, Wang, David J., Comte-Walters, Susana, Johnson, Roger H., Oberholtzer, Nathaniel, Nishimura, Michael I., Gygi, Steven P., Mehta, Anand, Guttridge, Denis C., Ball, Lauren, Mehrotra, Shikhar, Sicinski, Piotr, Yu, Xue-Zhong, Wang, Haizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544673/
https://www.ncbi.nlm.nih.gov/pubmed/37000627
http://dx.doi.org/10.1016/j.celrep.2023.112314