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Identification and quantification of (poly)phenol and methylxanthine metabolites in human cerebrospinal fluid: evidence of their ability to cross the BBB

Increasing evidence suggests that dietary (poly)phenols and methylxanthines have neuroprotective effects; however, little is known about whether they can cross the blood–brain barrier (BBB) and exert direct effects on the brain. We investigated the presence of (poly)phenol and methylxanthine metabol...

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Detalles Bibliográficos
Autores principales: Le Sayec, Melanie, Carregosa, Diogo, Khalifa, Khadija, de Lucia, Chiara, Aarsland, Dag, Santos, Cláudia N., Rodriguez-Mateos, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544810/
https://www.ncbi.nlm.nih.gov/pubmed/37701930
http://dx.doi.org/10.1039/d3fo01913f