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Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind to the same epitope
The function of an antibody is intrinsically linked to the epitope it engages. Clonal clustering methods, based on sequence identity, are commonly used to group antibodies that will bind to the same epitope. However, such methods neglect the fact that antibodies with highly diverse sequences can exh...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10544996/ https://www.ncbi.nlm.nih.gov/pubmed/37790877 http://dx.doi.org/10.3389/fmolb.2023.1237621 |