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Mechanistic multiscale modelling of energy metabolism in human astrocytes reveals the impact of morphology changes in Alzheimer’s Disease

Astrocytes with their specialised morphology are essential for brain homeostasis as metabolic mediators between blood vessels and neurons. In neurodegenerative diseases such as Alzheimer’s disease (AD), astrocytes adopt reactive profiles with molecular and morphological changes that could lead to th...

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Detalles Bibliográficos
Autores principales:	Farina, Sofia, Voorsluijs, Valérie, Fixemer, Sonja, Bouvier, David S., Claus, Susanne, Ellisman, Mark H., Bordas, Stéphane P. A., Skupin, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545114/ https://www.ncbi.nlm.nih.gov/pubmed/37729344 http://dx.doi.org/10.1371/journal.pcbi.1011464

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