Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease–related HCC

BACKGROUND: NAFLD caused by abnormalities in hepatic lipid metabolism is associated with an increased risk of developing HCC. The molecular mechanisms underlying the progression of NAFLD-related HCC are not fully understood. We investigated the molecular mechanism and role of KDM6B downregulation in...

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Detalles Bibliográficos
Autores principales: Hatano, Megumi, Akiyama, Yoshimitsu, Shimada, Shu, Yagi, Kohei, Akahoshi, Keiichi, Itoh, Michiko, Tanabe, Minoru, Ogawa, Yoshihiro, Tanaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545410/
https://www.ncbi.nlm.nih.gov/pubmed/37782459
http://dx.doi.org/10.1097/HC9.0000000000000277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545410/
https://www.ncbi.nlm.nih.gov/pubmed/37782459
http://dx.doi.org/10.1097/HC9.0000000000000277

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