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Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease–related HCC
BACKGROUND: NAFLD caused by abnormalities in hepatic lipid metabolism is associated with an increased risk of developing HCC. The molecular mechanisms underlying the progression of NAFLD-related HCC are not fully understood. We investigated the molecular mechanism and role of KDM6B downregulation in...
Autores principales: | Hatano, Megumi, Akiyama, Yoshimitsu, Shimada, Shu, Yagi, Kohei, Akahoshi, Keiichi, Itoh, Michiko, Tanabe, Minoru, Ogawa, Yoshihiro, Tanaka, Shinji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545410/ https://www.ncbi.nlm.nih.gov/pubmed/37782459 http://dx.doi.org/10.1097/HC9.0000000000000277 |
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