Betulinic Acid Attenuates Osteoarthritis via Limiting NLRP3 Inflammasome Activation to Decrease Interleukin-1β Maturation and Secretion

INTRODUCTION: Osteoarthritis (OA) is the most common degenerative joint disorder. Prior studies revealed that activation of NLRP3 inflammasome could promote the activation and secretion of interleukin-1β (IL-1β), which has an adverse effect on the progression of OA. Betulinic acid (BA) is a compound...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Wu, Yanglin, Liang, Ting, Zhou, Yunlong, Chen, Guangdong, He, Jiaheng, Ji, Chenchen, Liu, Peixin, Zhang, Chenhui, Lin, Jun, Shi, Kece, Luo, Zongping, Liu, Naicheng, Su, Xinlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545461/
https://www.ncbi.nlm.nih.gov/pubmed/37789884
http://dx.doi.org/10.1155/2023/3706421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545461/
https://www.ncbi.nlm.nih.gov/pubmed/37789884
http://dx.doi.org/10.1155/2023/3706421

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