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Betulinic Acid Attenuates Osteoarthritis via Limiting NLRP3 Inflammasome Activation to Decrease Interleukin-1β Maturation and Secretion
INTRODUCTION: Osteoarthritis (OA) is the most common degenerative joint disorder. Prior studies revealed that activation of NLRP3 inflammasome could promote the activation and secretion of interleukin-1β (IL-1β), which has an adverse effect on the progression of OA. Betulinic acid (BA) is a compound...
Autores principales: | Liu, Bo, Wu, Yanglin, Liang, Ting, Zhou, Yunlong, Chen, Guangdong, He, Jiaheng, Ji, Chenchen, Liu, Peixin, Zhang, Chenhui, Lin, Jun, Shi, Kece, Luo, Zongping, Liu, Naicheng, Su, Xinlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545461/ https://www.ncbi.nlm.nih.gov/pubmed/37789884 http://dx.doi.org/10.1155/2023/3706421 |
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