CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids

CRB1 gene mutations can cause early- or late-onset retinitis pigmentosa, Leber congenital amaurosis, or maculopathy. Recapitulating human CRB1 phenotypes in animal models has proven challenging, necessitating the development of alternatives. We generated human induced pluripotent stem cell (iPSC)-de...

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Detalles Bibliográficos
Autores principales: Buck, Thilo M., Quinn, Peter M.J., Pellissier, Lucie P., Mulder, Aat A., Jongejan, Aldo, Lu, Xuefei, Boon, Nanda, Koot, Daniëlle, Almushattat, Hind, Arendzen, Christiaan H., Vos, Rogier M., Bradley, Edward J., Freund, Christian, Mikkers, Harald M.M., Boon, Camiel J.F., Moerland, Perry D., Baas, Frank, Koster, Abraham J., Neefjes, Jacques, Berlin, Ilana, Jost, Carolina R., Wijnholds, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545476/
https://www.ncbi.nlm.nih.gov/pubmed/37541258
http://dx.doi.org/10.1016/j.stemcr.2023.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545476/
https://www.ncbi.nlm.nih.gov/pubmed/37541258
http://dx.doi.org/10.1016/j.stemcr.2023.07.001

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