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Integrated single cell analysis shows chronic alcohol drinking disrupts monocyte differentiation in the bone marrow

Chronic heavy alcohol drinking (CHD) rewires monocytes and macrophages toward heightened inflammatory states with compromised antimicrobial defenses that persist after 1-month abstinence. To determine whether these changes are mediated through alterations in the bone marrow niche, we profiled monocy...

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Detalles Bibliográficos
Autores principales: Lewis, Sloan A., Doratt, Brianna M., Qiao, Qi, Blanton, Madison, Grant, Kathleen A., Messaoudi, Ilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545484/
https://www.ncbi.nlm.nih.gov/pubmed/37657446
http://dx.doi.org/10.1016/j.stemcr.2023.08.001