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Integrated single cell analysis shows chronic alcohol drinking disrupts monocyte differentiation in the bone marrow
Chronic heavy alcohol drinking (CHD) rewires monocytes and macrophages toward heightened inflammatory states with compromised antimicrobial defenses that persist after 1-month abstinence. To determine whether these changes are mediated through alterations in the bone marrow niche, we profiled monocy...
Autores principales: | Lewis, Sloan A., Doratt, Brianna M., Qiao, Qi, Blanton, Madison, Grant, Kathleen A., Messaoudi, Ilhem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545484/ https://www.ncbi.nlm.nih.gov/pubmed/37657446 http://dx.doi.org/10.1016/j.stemcr.2023.08.001 |
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