DOT1L regulates lung developmental epithelial cell fate and adult alveolar stem cell differentiation after acute injury

AT2 cells harbor alveolar stem cell activity in the lung and can self-renew and differentiate into AT1 cells during homeostasis and after injury. To identify epigenetic pathways that control the AT2-AT1 regenerative response in the lung, we performed an organoid screen using a library of pharmacolog...

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Detalles Bibliográficos
Autores principales: Li, Shanru, Liberti, Derek, Zhou, Su, Ying, Yun, Kong, Jun, Basil, Maria C., Cardenas-Diaz, Fabian L., Shiraishi, Kazushige, Morley, Michael P., Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545485/
https://www.ncbi.nlm.nih.gov/pubmed/37595582
http://dx.doi.org/10.1016/j.stemcr.2023.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545485/
https://www.ncbi.nlm.nih.gov/pubmed/37595582
http://dx.doi.org/10.1016/j.stemcr.2023.07.006

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