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Archived rilpivirine-associated resistance mutations among ART-naive and virologically suppressed people living with HIV-1 subtype C in Botswana: implications for cabotegravir/rilpivirine use

OBJECTIVES: Pre-existing rilpivirine resistance-associated mutations (RVP-RAMs) have been found to predict HIV-1 virological failure in those switching to long-acting injectable cabotegravir/rilpivirine. We here evaluated the prevalence of archived RPV-RAMs in a cohort of people living with HIV (PWH...

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Detalles Bibliográficos
Autores principales: Maruapula, Dorcas, Moraka, Natasha O, Bareng, Ontlametse T, Mokgethi, Patrick T, Choga, Wonderful T, Seatla, Kaelo K, Kelentse, Nametso, Koofhethille, Catherine K, Zuze, Boitumelo J L, Gaolathe, Tendani, Pretorius-Holme, Molly, Makhema, Joseph, Novitsky, Vlad, Shapiro, Roger, Moyo, Sikhulile, Lockman, Shahin, Gaseitsiwe, Simani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545497/
https://www.ncbi.nlm.nih.gov/pubmed/37585352
http://dx.doi.org/10.1093/jac/dkad258