Lysosomal polygenic risk is associated with the severity of neuropathology in Lewy body disease

Intraneuronal accumulation of misfolded α-synuclein is the pathological hallmark of Parkinson’s disease and dementia with Lewy bodies, often co-occurring with variable degrees of Alzheimer’s disease related neuropathology. Genetic association studies have successfully identified common variants asso...

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Detalles Bibliográficos
Autores principales: Tunold, Jon-Anders, Tan, Manuela M X, Koga, Shunsuke, Geut, Hanneke, Rozemuller, Annemieke J M, Valentino, Rebecca, Sekiya, Hiroaki, Martin, Nicholas B, Heckman, Michael G, Bras, Jose, Guerreiro, Rita, Dickson, Dennis W, Toft, Mathias, van de Berg, Wilma D J, Ross, Owen A, Pihlstrøm, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545498/
https://www.ncbi.nlm.nih.gov/pubmed/37247383
http://dx.doi.org/10.1093/brain/awad183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545498/
https://www.ncbi.nlm.nih.gov/pubmed/37247383
http://dx.doi.org/10.1093/brain/awad183

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