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Pharmacokinetics and optimized dosing of dispersible and non-dispersible levofloxacin formulations in young children

BACKGROUND: Levofloxacin is used for treatment and prevention of rifampicin-resistant (RR)-TB in children. Recent data showed higher exposures with 100 mg dispersible compared with non-dispersible tablet formulations with potentially important dosing implications in children. We aimed to verify and...

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Detalles Bibliográficos
Autores principales: van der Laan, Louvina E, Hesseling, Anneke C, Schaaf, H Simon, Palmer, Megan, Draper, Heather R, Wiesner, Lubbe, Denti, Paolo, Garcia-Prats, Anthony J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545503/
https://www.ncbi.nlm.nih.gov/pubmed/37596982
http://dx.doi.org/10.1093/jac/dkad257