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A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria

OBJECTIVES: The rise of MDR Gram-negative bacteria (GNB), especially those resistant to last-resort drugs such as carbapenems and colistin, is a global health risk and calls for increased efforts to discover new antimicrobial compounds. We previously reported that polyimidazolium (PIM) compounds exh...

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Detalles Bibliográficos
Autores principales: Chen, Yahua, Yong, Melvin, Li, Ming, Si, Zhangyong, Koh, Chong Hui, Lau, Pearlyn, Chang, Yi Wei, Teo, Jeanette, Chan-Park, Mary B, Gan, Yunn-Hwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545527/
https://www.ncbi.nlm.nih.gov/pubmed/37671807
http://dx.doi.org/10.1093/jac/dkad274