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Convergent dopamine and ALK4 signaling to PCBP1 controls FosB alternative splicing and cocaine behavioral sensitization

ΔfosB is an alternatively spliced product of the FosB gene that is essential for dopamine‐induced reward pathways and that acts as a master switch for addiction. However, the molecular mechanisms of its generation and regulation by dopamine signaling are unknown. Here, we report that dopamine D1 rec...

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Detalles Bibliográficos
Autores principales: Krapacher, Favio A, Fernández‐Suárez, Diana, Andersson, Annika, Carrier‐Ruiz, Alvaro, Ibáñez, Carlos F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545536/
https://www.ncbi.nlm.nih.gov/pubmed/35730718
http://dx.doi.org/10.15252/embj.2022110721