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Intravenous injection of cyclosporin A loaded lipid nanocapsules fights inflammation and immune system activation in a mouse model of diabetic retinopathy

Inflammation and immune system activation are key pathologic events in the onset and escalation of diabetic retinopathy (DR). Both are driven by cytokines and complement originating from the retinal pigment epithelium (RPE). Despite the RPE’s pivotal role, there is no therapeutic tool to specificall...

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Detalles Bibliográficos
Autores principales: Bohley, Marilena, Dillinger, Andrea E., Braunger, Barbara M., Tamm, Ernst R., Goepferich, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545584/
https://www.ncbi.nlm.nih.gov/pubmed/37208562
http://dx.doi.org/10.1007/s13346-023-01350-7