Exogenous Ang-(1-7) inhibits autophagy via HIF-1α/THBS1/BECN1 axis to alleviate chronic intermittent hypoxia-enhanced airway remodelling of asthma

Obstructive sleep apnoea (OSA)-induced chronic intermittent hypoxia (CIH) has been considered a risk factor for severe asthma. Airway remodelling, which could be modulated by autophagy, plays a key role in severe asthma. However, the extent of autophagy’s involvement in CIH-potentiated airway remode...

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Detalles Bibliográficos
Autores principales: Zhou, Jian Ping, Wang, Yi, Li, Shi Qi, Zhang, Jia Qi, Lin, Ying Ni, Sun, Xian Wen, Zhou, Li Na, Zhang, Liu, Lu, Fang Ying, Ding, Yong Jie, Li, Qing Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545676/
https://www.ncbi.nlm.nih.gov/pubmed/37783703
http://dx.doi.org/10.1038/s41420-023-01662-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545676/
https://www.ncbi.nlm.nih.gov/pubmed/37783703
http://dx.doi.org/10.1038/s41420-023-01662-0

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