Fast functional mapping of ligand-gated ion channels

Ligand-gated ion channels are formed by three to five subunits that control the opening of the pore in a cooperative fashion. We developed a microfluidic chip-based technique for studying ion currents and fluorescence signals in either excised membrane patches or whole cells to measure activation an...

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Detalles Bibliográficos
Autores principales: Schmauder, Ralf, Eick, Thomas, Schulz, Eckhard, Sammler, Günther, Voigt, Elmar, Mayer, Günter, Ginter, Holger, Ditze, Günter, Benndorf, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545696/
https://www.ncbi.nlm.nih.gov/pubmed/37783870
http://dx.doi.org/10.1038/s42003-023-05340-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545696/
https://www.ncbi.nlm.nih.gov/pubmed/37783870
http://dx.doi.org/10.1038/s42003-023-05340-w

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