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Fast functional mapping of ligand-gated ion channels
Ligand-gated ion channels are formed by three to five subunits that control the opening of the pore in a cooperative fashion. We developed a microfluidic chip-based technique for studying ion currents and fluorescence signals in either excised membrane patches or whole cells to measure activation an...
Autores principales: | Schmauder, Ralf, Eick, Thomas, Schulz, Eckhard, Sammler, Günther, Voigt, Elmar, Mayer, Günter, Ginter, Holger, Ditze, Günter, Benndorf, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545696/ https://www.ncbi.nlm.nih.gov/pubmed/37783870 http://dx.doi.org/10.1038/s42003-023-05340-w |
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