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Scalable production of tissue-like vascularized liver organoids from human PSCs

The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed for a number of tissues, including the liver. Current organoid protocols are characterized by a reliance on extra...

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Detalles Bibliográficos
Autores principales: Harrison, Sean P., Siller, Richard, Tanaka, Yoshiaki, Chollet, Maria Eugenia, de la Morena-Barrio, María Eugenia, Xiang, Yangfei, Patterson, Benjamin, Andersen, Elisabeth, Bravo-Pérez, Carlos, Kempf, Henning, Åsrud, Kathrine S., Lunov, Oleg, Dejneka, Alexandr, Mowinckel, Marie-Christine, Stavik, Benedicte, Sandset, Per Morten, Melum, Espen, Baumgarten, Saphira, Bonanini, Flavio, Kurek, Dorota, Mathapati, Santosh, Almaas, Runar, Sharma, Kulbhushan, Wilson, Steven R., Skottvoll, Frøydis S., Boger, Ida C., Bogen, Inger Lise, Nyman, Tuula A., Wu, Jun Jie, Bezrouk, Ales, Cizkova, Dana, Corral, Javier, Mokry, Jaroslav, Zweigerdt, Robert, Park, In-Hyun, Sullivan, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545717/
https://www.ncbi.nlm.nih.gov/pubmed/37653039
http://dx.doi.org/10.1038/s12276-023-01074-1