Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence

Persistence of HIV in people living with HIV (PWH) on suppressive antiretroviral therapy (ART) has been linked to physiological mechanisms of CD4+ T cells. Here, in the same 37 male PWH on ART we measure longitudinal kinetics of HIV DNA and cell turnover rates in five CD4 cell subsets: naïve (T(N)),...

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Detalles Bibliográficos
Autores principales: Reeves, Daniel B., Bacchus-Souffan, Charline, Fitch, Mark, Abdel-Mohsen, Mohamed, Hoh, Rebecca, Ahn, Haelee, Stone, Mars, Hecht, Frederick, Martin, Jeffrey, Deeks, Steven G., Hellerstein, Marc K., McCune, Joseph M., Schiffer, Joshua T., Hunt, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545742/
https://www.ncbi.nlm.nih.gov/pubmed/37783718
http://dx.doi.org/10.1038/s41467-023-41521-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545742/
https://www.ncbi.nlm.nih.gov/pubmed/37783718
http://dx.doi.org/10.1038/s41467-023-41521-1

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