Velusetrag rescues GI dysfunction, gut inflammation and dysbiosis in a mouse model of Parkinson’s disease

In patients with Parkinson’s disease (PD), constipation is common, and it appears in a prodromal stage before the hallmark motor symptoms. The present study aimed to investigate whether Velusetrag, a selective 5‑HT4 receptor agonist, may be a suitable candidate to improve intestinal motility in a mo...

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Detalles Bibliográficos
Autores principales: Grigoletto, Jessica, Miraglia, Fabiana, Benvenuti, Laura, Pellegrini, Carolina, Soldi, Sara, Galletti, Serena, Cattaneo, Antonino, Pich, Emilio Merlo, Grimaldi, Maria, Colla, Emanuela, Vesci, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545757/
https://www.ncbi.nlm.nih.gov/pubmed/37783672
http://dx.doi.org/10.1038/s41531-023-00582-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545757/
https://www.ncbi.nlm.nih.gov/pubmed/37783672
http://dx.doi.org/10.1038/s41531-023-00582-1

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