NAD(+) metabolism is a key modulator of bacterial respiratory epithelial infections

Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic, proteomic and metabolic level. We found the NAD(+) salvage pathway to be dysregulate...

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Detalles Bibliográficos
Autores principales: Klabunde, Björn, Wesener, André, Bertrams, Wilhelm, Beinborn, Isabell, Paczia, Nicole, Surmann, Kristin, Blankenburg, Sascha, Wilhelm, Jochen, Serrania, Javier, Knoops, Kèvin, Elsayed, Eslam M., Laakmann, Katrin, Jung, Anna Lena, Kirschbaum, Andreas, Hammerschmidt, Sven, Alshaar, Belal, Gisch, Nicolas, Abu Mraheil, Mobarak, Becker, Anke, Völker, Uwe, Vollmeister, Evelyn, Benedikter, Birke J., Schmeck, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545792/
https://www.ncbi.nlm.nih.gov/pubmed/37783679
http://dx.doi.org/10.1038/s41467-023-41372-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545792/
https://www.ncbi.nlm.nih.gov/pubmed/37783679
http://dx.doi.org/10.1038/s41467-023-41372-w

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