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Reliable multiplex generation of pooled induced pluripotent stem cells

Reprogramming somatic cells into pluripotent stem cells (iPSCs) enables the study of systems in vitro. To increase the throughput of reprogramming, we present induction of pluripotency from pooled cells (iPPC)—an efficient, scalable, and reliable reprogramming procedure. Using our deconvolution algo...

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Detalles Bibliográficos
Autores principales: Smullen, Molly, Olson, Meagan N., Reichert, Julia M., Dawes, Pepper, Murray, Liam F., Baer, Christina E., Wang, Qi, Readhead, Benjamin, Church, George M., Lim, Elaine T., Chan, Yingleong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545906/
https://www.ncbi.nlm.nih.gov/pubmed/37751688
http://dx.doi.org/10.1016/j.crmeth.2023.100570