Accurate age prediction from blood using a small set of DNA methylation sites and a cohort-based machine learning algorithm

Chronological age prediction from DNA methylation sheds light on human aging, health, and lifespan. Current clocks are mostly based on linear models and rely upon hundreds of sites across the genome. Here, we present GP-age, an epigenetic non-linear cohort-based clock for blood, based upon 11,910 me...

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Detalles Bibliográficos
Autores principales: Varshavsky, Miri, Harari, Gil, Glaser, Benjamin, Dor, Yuval, Shemer, Ruth, Kaplan, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545910/
https://www.ncbi.nlm.nih.gov/pubmed/37751697
http://dx.doi.org/10.1016/j.crmeth.2023.100567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545910/
https://www.ncbi.nlm.nih.gov/pubmed/37751697
http://dx.doi.org/10.1016/j.crmeth.2023.100567

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