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Accurate age prediction from blood using a small set of DNA methylation sites and a cohort-based machine learning algorithm
Chronological age prediction from DNA methylation sheds light on human aging, health, and lifespan. Current clocks are mostly based on linear models and rely upon hundreds of sites across the genome. Here, we present GP-age, an epigenetic non-linear cohort-based clock for blood, based upon 11,910 me...
Autores principales: | Varshavsky, Miri, Harari, Gil, Glaser, Benjamin, Dor, Yuval, Shemer, Ruth, Kaplan, Tommy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545910/ https://www.ncbi.nlm.nih.gov/pubmed/37751697 http://dx.doi.org/10.1016/j.crmeth.2023.100567 |
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