Recapitulation of patient-specific 3D chromatin conformation using machine learning

Regulatory networks containing enhancer-gene edges define cellular states. Multiple efforts have revealed these networks for reference tissues and cell lines by integrating multi-omics data. However, the methods developed cannot be applied for large patient cohorts due to the infeasibility of chroma...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Duo, Forbes, Andre Neil, Cohen, Sandra, Palladino, Ann, Karadimitriou, Tatiana, Khurana, Ekta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545938/
https://www.ncbi.nlm.nih.gov/pubmed/37673071
http://dx.doi.org/10.1016/j.crmeth.2023.100578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545938/
https://www.ncbi.nlm.nih.gov/pubmed/37673071
http://dx.doi.org/10.1016/j.crmeth.2023.100578

Ejemplares similares