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Recapitulation of patient-specific 3D chromatin conformation using machine learning
Regulatory networks containing enhancer-gene edges define cellular states. Multiple efforts have revealed these networks for reference tissues and cell lines by integrating multi-omics data. However, the methods developed cannot be applied for large patient cohorts due to the infeasibility of chroma...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545938/ https://www.ncbi.nlm.nih.gov/pubmed/37673071 http://dx.doi.org/10.1016/j.crmeth.2023.100578 |