EGFR-T790M Mutation–Derived Interactome Rerouted EGFR Translocation Contributing to Gefitinib Resistance in Non-Small Cell Lung Cancer

Secondary mutation, T790M, conferring tyrosine kinase inhibitors (TKIs) resistance beyond oncogenic epidermal growth factor receptor (EGFR) mutations presents a challenging unmet need. Although TKI-resistant mechanisms are intensively investigated, the underlying responses of cancer cells adapting d...

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Detalles Bibliográficos
Autores principales: Wu, Pei-Shan, Lin, Miao-Hsia, Hsiao, Jye-Chian, Lin, Pei-Yi, Pan, Szu-Hua, Chen, Yu-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545940/
https://www.ncbi.nlm.nih.gov/pubmed/37495186
http://dx.doi.org/10.1016/j.mcpro.2023.100624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545940/
https://www.ncbi.nlm.nih.gov/pubmed/37495186
http://dx.doi.org/10.1016/j.mcpro.2023.100624

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