Mechanistic insights into MARK4 inhibition by galantamine toward therapeutic targeting of Alzheimer’s disease

Introduction: Hyperphosphorylation of tau is an important event in Alzheimer’s disease (AD) pathogenesis, leading to the generation of “neurofibrillary tangles,” a histopathological hallmark associated with the onset of AD and related tauopathies. Microtubule-affinity regulating kinase 4 (MARK4) is...

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Detalles Bibliográficos
Autores principales: Adnan, Mohd, DasGupta, Debarati, Anwar, Saleha, Shamsi, Anas, Siddiqui, Arif Jamal, Snoussi, Mejdi, Bardakci, Fevzi, Patel, Mitesh, Hassan, Md Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546050/
https://www.ncbi.nlm.nih.gov/pubmed/37795023
http://dx.doi.org/10.3389/fphar.2023.1276179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546050/
https://www.ncbi.nlm.nih.gov/pubmed/37795023
http://dx.doi.org/10.3389/fphar.2023.1276179

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