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Single-cell sequencing of tumor-associated macrophages in a Drosophila model

INTRODUCTION: Tumor-associated macrophages may act to either limit or promote tumor growth, yet the molecular basis for either path is poorly characterized. METHODS: We use a larval Drosophila model that expresses a dominant-active version of the Ras-oncogene (Ras(V12)) to study dysplastic growth du...

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Detalles Bibliográficos
Autores principales: Khalili, Dilan, Mohammed, Mubasher, Kunc, Martin, Sindlerova, Martina, Ankarklev, Johan, Theopold, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546068/
https://www.ncbi.nlm.nih.gov/pubmed/37795097
http://dx.doi.org/10.3389/fimmu.2023.1243797