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Azetidine synthesis by La(OTf)(3)-catalyzed intramolecular regioselective aminolysis of cis-3,4-epoxy amines

Azetidine is a prevalent structural motif found in various biologically active compounds. In this research paper, we report La(OTf)(3)-catalyzed intramolecular regioselective aminolysis of cis-3,4-epoxy amines to afford azetidines. This reaction proceeded in high yields even in the presence of acid-...

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Detalles Bibliográficos
Autores principales: Kuriyama, Yuse, Sasano, Yusuke, Iwabuchi, Yoshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546187/
https://www.ncbi.nlm.nih.gov/pubmed/37795386
http://dx.doi.org/10.3389/fchem.2023.1251299