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Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans

INTRODUCTION: Vascular dysfunction and chronic inflammation are characteristics of obesity-induced adipose tissue dysfunction. Proinflammatory cytokines can drive an endothelial-to-mesenchymal transition (EndoMT), where endothelial cells undergo a phenotypic switch to mesenchymal-like cells that are...

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Detalles Bibliográficos
Autores principales: Chavkin, Nicholas W., Vippa, Tanvi, Jung, Changhee, McDonnell, Stephanie, Hirschi, Karen K., Gokce, Noyan, Walsh, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546194/
https://www.ncbi.nlm.nih.gov/pubmed/37795485
http://dx.doi.org/10.3389/fcvm.2023.1264479