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Synergistic regulation of Notch signaling by different O-glycans promotes hematopoiesis

Glycosylation of Notch receptors by O-fucose glycans regulates Notch ligand binding and Notch signaling during hematopoiesis. However, roles in hematopoiesis for other O-glycans that modify Notch receptors have not been determined. Here we show that the EGF domain specific GlcNAc transferase EOGT is...

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Detalles Bibliográficos
Autores principales: Tanwar, Ankit, Stanley, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546201/
https://www.ncbi.nlm.nih.gov/pubmed/37795096
http://dx.doi.org/10.3389/fimmu.2023.1097332