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CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia-induced invasion and therapeutic resistance
Glioblastoma (GBM) is the most common and malignant primary brain tumor affecting adults and remains incurable. The mitochondrial coiled-coil-helix-coiled-coi l-helix domain-containing protein 2 (CHCHD2) has been demonstrated to mediate mitochondrial respiration, nuclear gene expression and cell mig...
Autores principales: | Lumibao, Jan C., Haak, Payton L., Kolossov, Vladimir L., Chen, Jee-Wei Emily, Stutchman, Jeremy, Ruiz, Alejandra, Sivaguru, Mayandi, Sarkaria, Jann N., Harley, Brendan A.C., Steelman, Andrew J., Gaskins, H. Rex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546377/ https://www.ncbi.nlm.nih.gov/pubmed/37654190 http://dx.doi.org/10.3892/ijo.2023.5565 |
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