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Comprehensive immunophenotyping of solid tumor-infiltrating immune cells reveals the expression characteristics of LAG-3 and its ligands

BACKGROUND: Immune cell expression profiling from patient samples is critical for the successful development of immuno-oncology agents and is useful to understand mechanism-of-action, to identify exploratory biomarkers predictive of response, and to guide treatment selection and combination therapy...

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Detalles Bibliográficos
Autores principales: Garman, Bradley, Jiang, Can, Daouti, Sherif, Kumar, Sanah, Mehta, Priyanka, Jacques, Miye K., Menard, Laurence, Manjarrez-Orduno, Nataly, Dolfi, Sonia, Mukherjee, Piali, Rai, Sharmila Chamling, Lako, Ana, Koenitzer, Jennifer D., David, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546411/
https://www.ncbi.nlm.nih.gov/pubmed/37795090
http://dx.doi.org/10.3389/fimmu.2023.1151748